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MedSchool Forums USMLE QBank A 5-year-old boy is being evaluated for recurrent epistaxis and other abnormal bleeding episodes, including excessive bleeding from the umbilical cord at birth. Laboratory studies reveal the following: decreased hemoglobin (with microcytic hypochromic red cell indices), normal platelet count, markedly prolonged prothrombin time (PT) and partial thromboplastin time (PTT), and unmeasurable thrombin time (TT). Platelet aggregation studies reveal a normal platelet response to ristocetin, but with other substances (including collagen, ADP, and epinephrine), this patient’s platelets exhibit a primary wave defect. Based on these findings, which of the following is the most likely diagnosis?
Spoiler for Answer:
Gray platelet syndrome

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Old 03-10-08, 07:21   #1
aniana
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Old 24-02-09, 06:38   #2
crazy_awper
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